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Ebola virus disease (EVD) with an average fatality rate of around 50 percent, has been infecting people from time to time, leading to outbreaks in several African countries. Risk of Advanced Cancers: Evolution to Blame? We found that the envelope protein of Ebola virus undergoes a drastic increase in certain mutations within bat cells, but this was not found in human cells. Ebola, SARS, and rabies all kill their hosts pretty quickly. Viruses depend on a living host for their survival and have natural reservoirs -- a hosting animal species in which a virus naturally lives and reproduces without causing disease. These are the familiar symptoms of Ebola, a deadly virus currently wreaking havoc across West Africa. Ebola is a rare disease impacting humans and other primates. It is thought that fruit bats of the Pteropodidae family are natural Ebola virus hosts. Questions? "We identified a number of meaningful differences in how the Ebola virus evolves when placed in a human cell line relative to a bat cell line," Bukreyev said. Why Bats Are Breeding Grounds for Deadly Diseases Like Ebola and SARS Bats are the source of more dangerous viruses than any other mammal. 1. Materials provided by University of Texas Medical Branch at Galveston. The infectious guano could have transmitted Ebola to humans or to another intermediate vector. Why doesn't Ebola cause disease in bats, as it does in people?. How can bats live with these viruses year after year? Well, that’s complicated. They assessed changes in mutation rates and the structure of Ebola virus populations repeatedly in both bat and human cell lines using an ultra-deep genetic sequencing. Viral infection in these bats leads to a swift response that walls the virus out of cells. www.sciencedaily.com/releases/2020/08/200818142147.htm (accessed December 12, 2020). The study suggests that the Ebola virus and bats can live together harmoniously because of the bat cell's ability to induce changes in the virus that make it less capable of harm. Ebola is introduced into the human population through close contact with the blood, secretions, organs or other bodily fluids of infected animals such as fruit bats, chimpanzees, gorillas, monkeys, forest antelope or porcupines found ill or dead or in the rainforest. Because of this, Ebola and similar viruses have a remarkable ability to adapt to and replicate in new environments. They are thought to be the natural reservoir for the Ebola virus. Though bats and other mammals can harbor the virus, they may not show any symptoms of the disease. Views expressed here do not necessarily reflect those of ScienceDaily, its staff, its contributors, or its partners. Fever, vomiting, a raised rash and weight loss. Like most other RNA viruses, Ebola's molecules are structured in a way that makes them more prone to genomic errors and mutations than other types of viruses. This study is now available in Cell Reports. This technology can be very useful in studying, and perhaps shaping, the evolution of emerging viruses, like SARS-CoV-2, the virus responsible for COVID-19. "Why doesn't Ebola cause disease in bats, as it does in people?." This study is now available in Cell Reports. "For instance, the RNA editing enzyme called ADAR within bat cells play a greater role in the replication and evolution of the Ebola virus than do such enzymes in human cells. Bats legitimately do harbor more sorts of viruses than other mammals and many of these viruses have proven to be zoonotic, yet as to whether they spread disease (or even are really the ultimate source of Ebola or Covid 19), the evidence is more exiguous. 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